Dietary <scp>l</scp>-glutamic acid N,N-diacetic acid improves short-term maintenance of zinc homoeostasis in a model of subclinical zinc deficiency in weaned piglets

Abstract This study compared the Zn response in selected tissues of weaned piglets fed L-glutamic acid, N,N-diacetic acid (GLDA), while challenged with short-term subclinical deficiency (SZD). During a total experimental period eight days, 96 were restrictively (450 g/d) high phytate (9 g/kg) diet containing added at 0, 5, 10, 15, 20, 25, 45 and 75 mg/kg without 200 GLDA. No animals showed signs clinical no phenotypical differences observed. Broken line analysis status parameters such as liver apparently absorbed indicated that gross requirement threshold was around 55 diet. Supplementation above this led to saturation linear increase Zn. Bone serum responded dose fashion, likely due time-frame homoeostatic adaptation. Inclusion GLDA into diets yielded higher intercept for bone ( P &lt; 0·05). Liver accumulation MT1A gene expression receiving 0·05), indicating influx. indicates strong chelator mitigates negative effects plant-based diets, by sustaining solubility, thereby improving nutritional availability.